Aspirin causes stomach bleeding due to its anti-clotting effect due to nonselective binding and inhibition to COX-1 and COX-2; see the list of https://en.wikipedia.org/wiki/Aspirin#Adverse_effects to see all the complications that arise from this relatively innocuous drug. 43 deaths in the US in a single year (mostly people taking the drug as a poison). See details in https://en.wikipedia.org/wiki/Salicylate_poisoning showing the all the kinds of human biology aspirin interacts with that don't directly contribute to pain suppression. The main reason for fewer people dying from aspirin was a shift to other drugs.
Millions of people use aspirin everyday to relieve aches and pains. 43 deaths is nothing compared to the benefits, especially since those people are intentionally overdosing with the intention of killing themselves.
I don't think that this is GP's point. The point is rather that biology is complex and solutions to biological problems are always complex even if they are accompanied by a simple narrative.
Some of us are explicitly forbidden to take aspirin by their Dr. so the population of asprin takers is biased towards a cohort for whom asprin is safe.
A lot more people die from Tylenol, and millions accumulate damage to their livers, but it is still OTC, and people believe it's less dangerous than Aspirin.
Except that for women that are pregnant or nursing and babies under 6 months old, Tylenol _is_ less dangerous than Aspirin. (It's the only OTC painkiller or antipyretic available that's considered safe.)
Which kinda leads us back to the greater point here... There are no simple answers to complex biological problems.
Probably, but the other damage from Tylenol is that it's been misused to lower fevers that don't need to be lowered and thus disarming the immune system.
That's a huge misconception and poor science. In fact, enteric-coated aspirin is worse as it could cause bleeding in the intestines, which is worse. There are plenty of studies that show taking aspirin with vitamin C or DGL does not cause bleeding! I think taking it alongside collagen/gelatin also prevents bleeding.
There was a sublingual form, which I cannot find (Fasprin). Also, there's Vazalore, which might be liposomal. I don't know, but the effervescent Aspirin C by Bayer is amazing! It works very well for gargles for sour throat, too!
