Last time I tried this maybe two years ago on Mac, there were some quirks/peculiarities/funkiness (can’t remember offhand what they were now a few years later), and while a liked it a lot I stopped using it because of that. Has the experience improved on the Mac or gotten ironed out since then?
One thing I needed to do in iTerm2 to get some of the Alt- commands to work was to change the option keys from "Normal" to "Esc+". (Settings -> "Profiles" tab -> "Keys" sub-tab -> Click "Esc+" radio for Option Keys.