I think you can pull some of the good stuff from here that you need and leave the stuff you don't.
As for designing websites in photoshop, at work we do it in keynote. It works surprisingly well and you can use mocks for presentations too! reference -> http://blog.swixhq.com/designing-swix-with-keynote/
OmniGraffle is also a great tool for wireframing and simple web graphics. Every time I complete a task without opening Photoshop, I want to give OmniGraffle a high five.
I'm not designer, I wouldn't even class myself as a developer, but like everyone else I have a few web projects on the go. I've been searching for a low overhead way of getting a design mock-up down and your keynote idea hits it on the head.
Really being a hacker, I just want to mock-up a design that isn't butt ugly and for the tools to get the hell out of my way so I can start cutting code.
Keynote is a great, flexible application. I like to use it for wireframing, and then use Photoshop to create the individual page graphics (rather than designing the whole site layout in there).
As for designing websites in photoshop, at work we do it in keynote. It works surprisingly well and you can use mocks for presentations too! reference -> http://blog.swixhq.com/designing-swix-with-keynote/